免疫治療可激活系統(tǒng)性抗腫瘤免疫效應、抑制腫瘤生長、轉(zhuǎn)移和復發(fā),已在臨床腫瘤治療方面表現(xiàn)出巨大潛力。然而,腫瘤細胞通常表現(xiàn)出較低的免疫原性,使得目前免疫治療策略的效率較低。鐵死亡是近年來發(fā)現(xiàn)的一種鐵依賴的脂質(zhì)過氧化引起的新型細胞死亡方式,鐵死亡相關過氧化脂質(zhì)可作為一種“發(fā)現(xiàn)我”的信號,促進樹突狀細胞對腫瘤抗原的識別、吞噬和處理,并將腫瘤相關抗原呈遞給CD8+ T淋巴細胞,進而激活細胞毒性T淋巴細胞,增強腫瘤免疫治療?;谏鲜鲅芯勘尘埃袊茖W院上海藥物研究所于海軍團隊近期于Advanced Materials 期刊上發(fā)表了題目為“Acidity-Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer”的文章,提出利用酸敏感遞藥系統(tǒng)協(xié)同誘導腫瘤細胞鐵死亡與免疫原性死亡,從而改善抗腫瘤免疫應答的策略。
本文中使用了欣博盛小鼠IL-6, TNF-α and IFN-γ ELISA Kits,檢測腫瘤組織勻漿液中細胞因子的水平。
1.文章題目:Acidity-Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer.
期 刊:Advanced Materials(影響因子:30.849)
發(fā)表時間:25 June 2021
作 者:Song R, Li T, Ye J, et al.
作者單位:中國科學院上海藥物研究所
使用產(chǎn)品:Mouse IL-6, TNF-α and IFN-γ ELISA Kits
樣本類型:腫瘤組織
https://pubmed.ncbi.nlm.nih.gov/34170581/
2.文章題目:Binding of Benzo [a] pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
期 刊:ACS nano(影響因子:15.881)
發(fā)表時間:14 June 2021
作 者:Ma J, Liu X, Yang Y, et al.
作者單位:中國科學院生態(tài)環(huán)境研究中心
使用產(chǎn)品:Mouse IL-6 ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/34124884/
3.文章題目:Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy.
期 刊:Biomaterials(影響因子:12.479)
發(fā)表時間:24 June 2021
作 者:Feng Y, Xie X, Zhang H, et al.
作者單位:電子科技大學
使用產(chǎn)品:Mouse IL-6, IL-10, TNF-α and IFN-γ ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34186239/
4.文章題目:A small molecule HIF-1α stabilizer that accelerates diabetic wound healing.
期 刊:Nature communications(影響因子:12.121)
發(fā)表時間:7 June 2021
作 者:Li G, Ko C N, Li D, et al.
作者單位:澳門大學
使用產(chǎn)品:Mouse VEGF ELISA Kit
樣本類型:大腦黑質(zhì)
https://pubmed.ncbi.nlm.nih.gov/34099651/
5.文章題目:The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response.
期 刊:Cell Discovery(影響因子:10.849)
發(fā)表時間:22 June 2021
作 者:Li C, Feng L, Luo W W, et al.
作者單位:武漢大學中南醫(yī)院
使用產(chǎn)品:Mouse IP-10/CXCL10 ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/34155193/
6.文章題目:Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease.
期 刊:Journal of neuroinflammation(影響因子:8.322)
發(fā)表時間:11 June 2021
作 者:Sun X, Li L, Dong Q X, et al.
作者單位:中國科學院過程工程研究所
使用產(chǎn)品:Mouse IL-1β and TNF-α ELISA Kits
樣本類型:大腦組織
https://pubmed.ncbi.nlm.nih.gov/34116706/
7.文章題目:Methyl Diet Enhanced Sepsis-Induced Mortality Through Altering Gut Microbiota.
期 刊:Journal of Inflammation Research(影響因子:6.922)
發(fā)表時間:29 June 2021
作 者:Yu C, Zhu X, Zheng C, et al.
作者單位:上海中醫(yī)藥大學曙光醫(yī)院
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA Kits
樣本類型:腹腔灌洗液
https://pubmed.ncbi.nlm.nih.gov/34276224/
8.文章題目:Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
期 刊:Oxidative Medicine and Cellular Longevity(影響因子:6.543)
發(fā)表時間:15 June 2021
作 者:Yang D, Zuo Q, Wang T, et al.
作者單位:四川大學華西醫(yī)院
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA Kits
樣本類型:支氣管肺泡灌洗液
https://pubmed.ncbi.nlm.nih.gov/34221235/
9.文章題目:Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness.
期 刊:Ecotoxicology and Environmental Safety(影響因子:6.291)
發(fā)表時間:24 June 2021
作 者:Lu X, Zhang H, Wang M, et al.
作者單位:河北醫(yī)科大學第二醫(yī)院
使用產(chǎn)品:Human and mouse IL-1β, IL-6 and IL-8 ELISA Kits
樣本類型:小鼠支氣管肺泡灌洗液
https://pubmed.ncbi.nlm.nih.gov/34175826/
10.文章題目:High Neutrophil to Lymphocyte Ratio and Its Gene Signatures Correlate With Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction.
期 刊:Frontiers in Cardiovascular Medicine(影響因子:6.05)
發(fā)表時間:24 June 2021
作 者:Bai B, Cheng M, Jiang L, et al.
作者單位:深圳市第二人民醫(yī)院
使用產(chǎn)品:Human IL-1β, IL-6, IL-10, TNF-α, sICAM-1 and MMP-9 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34250033/
11.文章題目:Targeting hypoxia for sensitization of tumors to apoptosis enhancement through supramolecular biohybrid bacteria.
期 刊:International Journal of Pharmaceutics(影響因子:5.875)
發(fā)表時間:22 June 2021
作 者:Wu Y, Li Q, Liu Y, et al.
作者單位:海南大學
使用產(chǎn)品:Mouse TNF-α, IL-2 and IFN-γ ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34166726/
12.文章題目:Resveratrol Ameliorates Cardiac Remodeling in a Murine Model of Heart Failure With Preserved Ejection Fraction.
期 刊:Frontiers in Pharmacology(影響因子:5.81)
發(fā)表時間:10 June 2021
作 者:Zhang L, Chen J, Yan L, et al.
作者單位:武漢市中心醫(yī)院
使用產(chǎn)品:Mouse IL-1β and TNF-α ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34177571/
13.文章題目:Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
期 刊:NanoImpact(影響因子:5.316)
發(fā)表時間:15 June 2021
作 者:Liu Y, Hu Q, Huang C, et al.
作者單位:南華大學
使用產(chǎn)品:Human IL-6 ELISA Kit
https://www.sciencedirect.com/science/article/abs/pii/S2452074821000422
14.文章題目:Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition.
期 刊:Neuropharmacology(影響因子:5.25)
發(fā)表時間:3 June 2021
作 者:Yan H, Zhao H, Kang Y, et al.
作者單位:河北醫(yī)科大學
使用產(chǎn)品:Rat TNF-α ELISA Kit
樣本類型:大腦黑質(zhì)
https://pubmed.ncbi.nlm.nih.gov/34089729/
15.文章題目:Hydrogen sulfide attenuated sepsis-induced myocardial dysfunction through TLR4 pathway and endoplasmic reticulum stress.
期 刊:Frontiers in Physiology(影響因子:4.566)
發(fā)表時間:9 June 2021
作 者:Chen Y, Teng X, Hu Z, et al.
作者單位:河北醫(yī)科大學
使用產(chǎn)品:Mouse TNF-α and IL-1β ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34177611/
16.文章題目:Bis (ethylmaltolato) oxidovanadium (IV) attenuates amyloid-beta-mediated neuroinflammation by inhibiting NF-κB signaling pathway via a PPARγ-dependent mechanism.
期 刊:Metallomics(影響因子:4.526)
發(fā)表時間:14 June 2021
作 者:He Z, Li X, Han S, et al.
作者單位:深圳大學
使用產(chǎn)品:Mouse TNF-α, IL-1β and IL-6 ELISA Kits
樣本類型:海馬體
https://pubmed.ncbi.nlm.nih.gov/34124763/
17.文章題目:Mulberry (Morus atropurpurea Roxb.) leaf protein hydrolysates ameliorate dextran sodium sulfate-induced colitis via integrated modulation of gut microbiota and immunity.
期 刊:Journal of Functional Foods(影響因子:4.451)
發(fā)表時間:16 June 2021
作 者:Sun C, Tang X, Shao X, et al.
作者單位:暨南大學
使用產(chǎn)品:Mouse IL-6, TNF-α, IL-1β, IL-10 and IgA ELISA Kits
樣本類型:結腸組織(除IgA)
https://www.sciencedirect.com/science/article/pii/S1756464621002243
18.文章題目:Establishing a patient registry study database of dust mite allergic asthma in children: design, methodology and preliminary exploration.
期 刊:Annals of Translational Medicine(影響因子:3.932)
發(fā)表時間:15 June 2021
作 者:Zhou J, Li W, Wen X, et al.
作者單位:重慶醫(yī)科大學附屬兒童醫(yī)院
使用產(chǎn)品:Human IL-4, IL-5 and IL-13 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34277793/
19.文章題目:Tocopheryl quinone improves non-alcoholic steatohepatitis (NASH) associated dysmetabolism of glucose and lipids by upregulating the expression of glucagon-like peptide 1 (GLP-1) via restoring the balance of intestinal flora in rats.
期 刊:Pharmaceutical Biology(影響因子:3.503)
發(fā)表時間:17 June 2021
作 者:Sun T, Zhang B, Ru Q, et al.
作者單位:浙江中醫(yī)藥大學第二臨床醫(yī)學院
使用產(chǎn)品:Rat IL-6 and TNF-α ELISA Kits
樣本類型:腸組織
https://pubmed.ncbi.nlm.nih.gov/34139927/
20.文章題目:Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
期 刊:Pulmonary Pharmacology & Therapeutics(影響因子:3.41)
發(fā)表時間:5 June 2021
作 者:Luo Y, Chen H, Huang R, et al.
作者單位:四川大學華西醫(yī)院
使用產(chǎn)品:Mouse IL-4, IL-6 and IL-13 ELISA Kits
樣本類型:肺組織
https://pubmed.ncbi.nlm.nih.gov/34102301/
21.文章題目:Overexpression of hepatocyte growth factor in dental pulp stem cells ameliorates the severity of psoriasis by reducing inflammatory responses.
期 刊:Stem Cells and Development(影響因子:3.272)
發(fā)表時間:22 June 2021
作 者:Meng H, Wei F, Zhou Y, et al.
作者單位:天津大學
使用產(chǎn)品:Human IFN-γ, IL-4, TGF-β1, IL-6 and HGF ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34155928/
22.文章題目:Gastric cancer cell-derived exosomes can regulate the biological functions of mesenchymal stem cells by inducing the expression of circular RNA circ_0004303.
期 刊:Stem Cells and Development(影響因子:3.272)
發(fā)表時間:7 June 2021
作 者:Ba L, Xue C, Li X, et al.
作者單位:中國醫(yī)學科學院北京協(xié)和醫(yī)學院
使用產(chǎn)品:Secondary (HRP)-conjugated antibodies
https://pubmed.ncbi.nlm.nih.gov/34098776/
23.文章題目:MiR-146a Negatively Regulates Aspergillus fumigatus-Induced TNF-α and IL-6 Secretion in THP-1 Macrophages.
期 刊:Mycopathologia(影響因子:2.574)
發(fā)表時間:4 June 2021
作 者:Tong J, Duan Z, Zeng R, et al.
作者單位:中國醫(yī)學科學院皮膚病研究所
使用產(chǎn)品:Human TNF-α and IL-6 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34089172/
24.文章題目:Effect of fibulin?5 on aldosterone?induced apoptosis in human ascending aortic smooth muscle cells.
期 刊:Experimental and Therapeutic Medicine(影響因子:2.447)
發(fā)表時間:23 June 2021
作 者:Yan Y, Liu X, Li X, et al.
作者單位:北京中醫(yī)藥大學東直門醫(yī)院
使用產(chǎn)品:Annexin V-FITC/PI apoptosis assay kit
https://pubmed.ncbi.nlm.nih.gov/34257709/
25.文章題目:miR?133a?3p regulates the proliferation and apoptosis of intestinal epithelial cells by modulating the expression of TAGLN2.
期 刊:Experimental and Therapeutic Medicine(影響因子:2.447)
發(fā)表時間:2 June 2021
作 者:Tian X, Li L, Fu G, et al.
作者單位:空軍軍醫(yī)大學唐都醫(yī)院
使用產(chǎn)品:Annexin V-FITC/PI apoptosis assay kit
https://pubmed.ncbi.nlm.nih.gov/34149870/